How E-Prescribing Improves Opioid Security and PDMP Compliance in Healthcare

Editorial Team
9 Min Read


Jessica Wagner, COO at RXNT

Based on latest CDC knowledge, opioids stay the driving pressure behind the overwhelming majority of U.S. drug overdose deaths. Whereas prescription charges have declined over the previous a number of years, opioid-related overdoses have truly risen once more since 2024, underscoring that the disaster has not eased, however shifted. At the moment’s problem isn’t simply stopping overprescribing; it’s navigating a extra complicated danger surroundings the place illicit medicine, prescription misuse, and affected person entry wants intersect.

How E-Prescribing Expertise is Lowering Opioid Misuse Throughout the U.S.

E-prescribing basically replaces handwritten or printed scripts with digitally transmitted orders. Nonetheless, overlooking it as merely “digitized paperwork” undermines its true potential. After we hyperlink healthcare suppliers and pharmacies by way of safe, interoperable methods, e-prescribing reduces paperwork errors, enhances prescription processing effectivity, and improves transparency with respect to a affected person’s remedy historical past.

With quick entry to affected person info, healthcare professionals can confirm allergy symptoms, establish overlapping remedies, and detect potential hostile drug interactions all earlier than finalizing their selections. This quick security verification reduces confusion and hold-ups related to e-prescribing workarounds and out of date documentation. Moreover, the shift to digital prescriptions considerably reduces the probability of prescription fraud, addressing an important problem within the context of opioid misuse.

Stopping Prescription Fraud with Tamper-Proof Digital Workflows

Prescription fraud has modified—what was a reasonably easy scheme, whereby scammers merely used stolen pads of prescriptions and solid medical doctors’ signatures, has graduated to id theft, with fraudsters utilizing stolen identities to fill the prescriptions.

To this finish, e-prescribing has built-in new safety features that improve id verification and block unauthorized entry. As an example, now we have been working with an organization that makes use of id verification instruments to make sure that the prescribers’ identities are verified earlier than a prescription is written. This further degree of safety helps decrease the chance of fraud with out compromising the effectivity of the prescribing course of.

Since all of the prescriptions are documented electronically, healthcare suppliers and pharmacists can simply catch unusual refill requests and odd prescriptions, and even evaluate what medicines the affected person is taking and is meant to be taking as per the information. To the builders of healthcare, this integration of safety and transparency is a step in the direction of a greater, extra dependable, and virtually fraud-immune prescribing system.

Integrating PDMP Knowledge Straight Into Prescribing Workflows

Certainly one of e-prescribing’s most impactful options is its streamlined integration with Prescription Drug Monitoring Applications (PDMPs). These important state-level databases function central repositories for monitoring managed substance prescriptions. Previously, accessing this significant info was a cumbersome, multi-step course of, forcing prescribers and dispensers to navigate disparate methods – a workflow inherently weak to delays and oversights. 

Trendy e-prescribing platforms streamline this by embedding PDMP checks straight inside the prescription course of. Ought to a affected person’s historical past point out latest opioid prescriptions, particularly from a number of prescribers, the system supplies a danger rating and detailed report that features prescription and prescriber particulars. This available knowledge permits clinicians to thoughtfully rethink opioid decisions, contemplate various ache administration methods, and implement stricter affected person monitoring. This enhanced transparency promotes a extra accountable healthcare ecosystem and actively combats potential drug diversion.

Lowering Excessive-Danger Opioid Prescriptions By way of Smarter Digital Instruments

In apply, healthcare organizations that undertake e-prescribing typically report a drop in doubtful opioid prescriptions. As a result of each order is tracked and simply audited, it turns into far easier to find out whether or not an opioid prescription is clinically warranted. The advantages prolong to all high-risk medicines, however given the scope of the opioid disaster, the influence right here is especially pronounced.

E-prescribing additionally nudges clinicians to think about the length and dosage of every opioid order. As an alternative of defaulting to a regular one-week provide, they could go for a shorter course if that’s ample for ache administration. A latest examine discovered that after implementing medical resolution assist alerts, there was a 27% discount within the common day provide of opioids prescribed to opioid-naïve sufferers. This demonstrates how e-prescribing not solely streamlines workflows but additionally actively influences prescribing behaviors, resulting in extra cautious opioid use.

Predicting Opioid Misuse Danger with AI-Pushed Prescribing Insights

E-prescribing has already modified the apply of opioid stewardship, however new know-how is enhancing it additional. New applied sciences are being developed that may assist analyze a affected person’s medical historical past, prescription patterns, and social elements to foretell who’s more than likely to misuse opioids. Current findings confirmed {that a} machine studying mannequin primarily based on the well being information was 90% correct in figuring out sufferers with excessive danger of opioid use dysfunction, which can assist clinicians to intervene earlier than the misuse of opioids results in habit. 

CDS instruments are growing quick and can change the best way prescriptions are dealt with. These methods can scan tons of of hundreds of knowledge factors in actual time. They’ll establish potential issues similar to drug interactions, duplicate therapies, and presumably substance use. A examine performed on CDS instruments built-in into EHRs was capable of present remedy alerts to the suppliers, which can assist in figuring out points similar to incorrect dosage, harmful drug interactions, and contraindications, which might result in remedy errors and danger to the affected person (PMC). 

But in lots of rural areas, e-prescribing adoption lags. Analysis exhibits, physicians in these communities typically face lengthy journey distances for sufferers, restricted ache administration alternate options, and regulatory constraints that complicate applicable prescribing. As a result of some sufferers can solely afford one journey to the physician, physicians could prescribe bigger portions to reduce logistical burdens, inadvertently growing the chance of misuse. In the meantime, tighter rules aiming to curb opioid abuse also can discourage cautious, individualized prescribing.

Bridging this digital and logistical hole is important. Extending e-prescribing infrastructure to underserved areas and pairing it with sturdy oversight and assets can be certain that sufferers obtain safer, data-driven ache administration options. Increasing pharmacy entry in these areas can be a essential element, as it may possibly scale back the necessity for bigger prescriptions by offering sufferers with extra frequent and handy entry to their medicines. There’s nonetheless vital floor to cowl, however with ongoing refinements in e-prescribing and a sharper give attention to communities that want extra assist, we’re shifting nearer to a future the place accountable prescribing is the common commonplace.


About Jessica Wagner

Jessica Wagner serves as RXNT’s Chief Working Officer, bringing a wealth of buyer perception, product data, and organizational background to her function. Ms. Wagner is dedicated to fixing complicated issues going through medical practices and billing organizations with easy options, which is why her staff is solely centered on offering software program that improves the every day operations of healthcare organizations to liberate time for what issues most: enhancing affected person care.

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